danuser lab

harvard medical school :: department of cell biology :: laboratory for computational cell biology

We study how mechanical and chemical signals integrate in space and time to control cytoskeleton dynamics and membrane trafficking. We develop a minimally-perturbing experimental approach that exploits the intrinsic heterogeneity of cell dynamic states to probe the hierarchy and kinetics of mechanochemical signaling cascades.

read our latest paper

Coordination of Rho GTPase activities during cell protrusion

Machacek, M. et al., Nature 461, 99-103 (3 September 2009)

news

January 7, 2010:: Immediate open position for a software developer.
October 1, 2009::Danuser and Hahn are awarded a Transformative R01 grant by NIH to develop new biosensors and mathematical modeling approaches for the study of large signaling networks.