“We study how mechanical and chemical signals integrate in space and time to control cytoskeleton dynamics and membrane trafficking. We develop a minimally-perturbing experimental approach that exploits the intrinsic heterogeneity of cell dynamic states to probe the hierarchy and kinetics of mechanochemical signaling cascades.” read our latest paper
Quantitative Imaging of Epithelial Cell Scattering Identifies Specific Inhibitors of Cell Motility and Cell-Cell Dissociation
Loerke, D. and le Duc, Q. et al., Science Signaling 5(231):rs5, 2012 read our collaborators' latest paper
Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility
Ng, M.R. et al., J. Cell Biol. 199(3) (October 2012) |
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news
| October 8, 2012 | :: | Sangyoon Han joins LCCB as a postdoctoral fellow. He will be working on the development of novel algorithms to numerically link extracellular and intracellular forces to model cytoskeleton material properties. |
| July 1, 2012 | :: | Alexis Lomakin receives a fellowship for 36 months from the Leukemia and Lymphoma Society to work on the project "Microtubule patterning in orchestrating cell polarity and morphogenetic behaviors." Congratulations! |
| June 1, 2012 | :: | Deepak Chittajallu joins LCCB as a postdoctoral fellow. He will be working on the development of novel algorithms for complex image segmentation and spatial clustering. |
| March 1, 2012 | :: | The postdoc position for intravital imaging is filled. |
| February 6, 2012 | :: | Nancy Costigliola joins LCCB as a postdoctoral fellow. She will be working on cell biological and live cell imaging based analyses of the roles of vimentin intermediate filaments in cell migration. |
| January 1, 2012 | :: | Youbean Oak joins LCCB as a MCB graduate student. She will be working on cell biological and live cell imaging based analyses of the roles of fascin in cancer cell migration. Kwonmoo Lee receives a fellowship for 24 months from the NIH to work on the project "Spatiotemporal Coordination of Formin and Arp2/3 in Epithelial Cell Migration." Congratulations! |
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